Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients

Index Predictive of Drug Resistant Tuberculosis (MDR-TB) on Tuberculosis Patients

TB-MDR, risk factors, Gresik District

The resistance of the M. Tuberculosis germ to anti-tuberculosis drugs is a state in which germs can no longer be killed by first-line medicine, such as isoniazid and rifampicin. Indonesia is in 8th place out of 27 countries that have a high burden of MDR-TB. Gresik district is not among the top 10 districts in East Java, which have the highest TB incidence, but Gresik was a district with the highest proportion of MDR-TB cases among TB cases in East Java in 2015. The research design of this study is case control. The sampling technique is simple random sampling. Based on the analysis using multiple logistic regression, the index of incidence of MDR-TB obtained as Drugs Swallowing Control p= 0.002, regularity p= 0.000, side effects of drugs p= 0.001, the result of previous treatment p= 0.000 and DM p= 0.001. This prediction index can predict the risk of MDR-TB occurring in Gresik with 90.2% sensitivity and 78.9% specificity with measurement accuracy is 84.1%. It can be concluded that the index of incidence of MDR-TB is 4.359 + 2.137 (Drugs Swallowing Control) + 2.885 (regularity) + 2.094 (drug side effects) + 1.926 (previous treatment) + 2.013 (diabetes mellitus).

Penulis 1 : Ariska Putri Hidayathillah
Penulis 2 : Chatarina Umbul W
Penulis 2 : Hari Basuki N

Proceedings of the 2nd International Symposium of Public Health. Vol 1. Hal 227-231
ISSN : 978-989-758-338-4
https://www.scitepress.or/ProceedingsDetails.aspx?ID=efBVUjPvQ5Q%3d&t=1

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